Research Area. Tissue Dissociation. Tissue Dissociation and Isolation. Cell Culture and Assay. Cell Sourcing and Isolation. Culture and Cryopreservation. Workflow Stages for Neuronal Research. Cell Culture. One of our representatives will be happy to help you by telephone or email. Please complete the form to contact us by email.
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Product Overview Trypsin is a clear, colorless-yellow, highly active bovine enzyme preparation, used to remove cells from the culture vessel surface into suspension. SDS - French. SDS - German. SDS - Italian. SDS - Spanish. SDS - Dutch. This is a gentler version than the standard concentration 0. Related Products Related Products. Product Applications This product is designed for use in the following research area s as part of the highlighted workflow stage s.
Research Area. Tissue Dissociation. Transfection and Selection. Expansion and Characterization. Workflow Stages for Neuronal Research. Cell Culture. View publication. Abstract The role of intermediate methylation states in DNA is unclear. Here, to comprehensively identify regions of intermediate methylation and their quantitative relationship with gene activity, we apply integrative and comparative epigenomics to 25 human primary cell and tissue samples.
These regions have an intermediate level of active chromatin marks and their associated genes have intermediate transcriptional activity. Exonic intermediate methylation correlates with exon inclusion at a level between that of fully methylated and unmethylated exons, highlighting gene context-dependent functions. We conclude that intermediate DNA methylation is a conserved signature of gene regulation and exon usage.
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